I know this is such a basic post. I am sorry for that. For the first time in over 20 years, I have developed 2 cold sores on my lip. I had one and it's dissipating and now another one is coming in. I can't believe this. I normally have them in my mouth, which is easier and better as these are unsightly and the one keeps bleeding. Sorry for TMI. Valtrex yet again, has made me horrible ill. What do you do for cold sores? I know Lysine is the basic tried and true treatment. Can anyone else shed some light? Do you use lysine or is there something else you know of? I am exhausted, too. I know my EBV is clearly acting up. The Valtrex caused my pain to skyrocket and it really didn't do that much because here I am developing another cold sore!