Full story: https://www.sciencedaily.com/releases/2016/06/160630144409.htmTreating autoimmune disease without harming normal immunity
Preclinical study shows that engineered T cells can selectively target the antibody-producing cells that cause autoimmune disease
Date:
June 30, 2016
Source:
University of Pennsylvania School of Medicine
Summary:
With potentially major implications for the future treatment of autoimmunity and related conditions, scientists have found a way to remove the subset of antibody-making cells that cause an autoimmune disease, without harming the rest of the immune system. They studied an autoimmune disease called pemphigus vulgaris, a condition in which a patient's own immune cells attack a protein called desmoglein-3 that normally adheres skin cells.