Transmission of another gammaretrovirus, Feline Leukemia Virus

The discovery of XMRV in respiratory secretions raises still more questions about possible transmission. Of course, until empirical and epidemiological studies are done, its all just conjecture. Most of the supposition Ive seen is based on the way HIV is transmitted. But HIV is a Lentivirus, while XMRV is a Gammaretrovirus. It makes sense to me that as long as were speculating, we might as well look at how another Gammaretrovirus is spread, not to mention how it acts in the body, so I looked up Feline Leukemia Virus (FeLV). I found a nice overview put out by the Cornell University School of Veterinary Medicine.
http://www.vet.cornell.edu/FHC/news/FeLV.htm

Here are some excerpts:

I might also mention that there is a vaccine against FeLV.

Theres also a largely unsourced Wikipedia article, which describes the symptoms of FeLV infection:
Loss of appetite, poor coat condition, infections of the skin, bladder and respiratory tract, oral disease, seizures, lymphadenopathy (swollen lymph nodes), skin lesions, fatigue, fever, weight loss, stomatitis, gingivitis, litter box avoidance, pancytopenia, poor grooming, reoccurring bacterial and viral illnesses, anemia, diarrhea, jaundice.

Sounds familiar, doesnt it? Well, maybe except for litter box avoidance. Although, now that I think of it, I do try to avoid litter boxes.

So Dr Wessely, are you feeling lucky? Do you want to put your money where your mouth is and have a lick from my ice cream cone?
Maybe the CDC should come out with a recommendation that people diagnosed with CFS should refrain from licking their friends until further research can be conducted.

Seriously, one of the most interesting parts (to me) is that some cats who are infected get sick and others don't. Wish I knew what the difference is. Maybe the ones who get sick have a sickness ideation.

 

I have been thinking for a few weeks that we should be comparing XMRV to FeLV instead of HIV.

Not as much because of type of retrovirus, but because almost all with HIV will die if not treated. Also, almost all with HIV will get sick.

Seems likely at this time that many with XMRV never get sick, a few get cancer and some get immune system problems (CFS). This seems to match FeLV moreso than HIV.

Tina

 

Very interesting post, Is there any evidence at all that Felv could jump the species barrier to humans ? thought i read it can not.

 

Very interesting, agreed. I especially am enjoying the idea of sick cat with sickness ideation. Great for a cartoonist...wish I were one.

 

Nope, no evidence that FeLV can infect humans.

 

This comes from Cornell University:

About 2-3 % of cats are infected with FeLV. In high risk cats, the rate is 13%.
Transmission can occur through mutual grooming, bites, sharing litter box or sharing water bowls. The virus only lives a couple of hours outside the body.

A kitten is more susceptible to infection after exposure than an adult cat.

FeLV is the number one cause of cancers in cats. It can cause blood disorders and weakened immune system, making cat vulnerable to every day fungi, bacteria, protozoa and viruses.

Two stages to FeLV. Stage one is early infection stage. Sometimes immune system can lodge an attack and eliminate virus from blood stream, thus preventing progression. Stage two includes persistent infection of the bone marrow. At this point, it is past the point of no return and "overwhelming majority" will have will be fighting the infection for the rest of their lives.

An infected cat should be kept indoors and away from other cats to prevent a secondary infection. Feed it nutritionally complete and balanced diet. Avoid raw food because of the bacteria and parasites.

In second stage, most infected cats succumb to a FeLV-related disease within two-three years. If the cat is already experiencing cancer, persistent fever,or weight loss, a much shorter survival is expected.

Tina

 

Ok thanks for that. had a lot of cats around the time my flu like illnesses started was reason for asking

 

Hi,

I realize that this is happening with me. I regularly have bacterial infections in my intestines, most probably due to the food I eat. Right now, I have it again, much blood in the stool, fever... Never had this before.

Oh my god...

OS.

 

These malingering cats need to snap out of it and get a job. These hypochondriac cats claim they're infected with a retroviral disease passed by saliva, but everyone knows a retrovirus can't pass through saliva!

 

I read in some book on ME that it seems some people get ME at the same time their pets have an ME-like illness.