The discovery of XMRV in respiratory secretions raises still more questions about possible transmission. Of course, until empirical and epidemiological studies are done, its all just conjecture. Most of the supposition Ive seen is based on the way HIV is transmitted. But HIV is a Lentivirus, while XMRV is a Gammaretrovirus. It makes sense to me that as long as were speculating, we might as well look at how another Gammaretrovirus is spread, not to mention how it acts in the body, so I looked up Feline Leukemia Virus (FeLV). I found a nice overview put out by the Cornell University School of Veterinary Medicine. http://www.vet.cornell.edu/FHC/news/FeLV.htm Here are some excerpts: I might also mention that there is a vaccine against FeLV. Theres also a largely unsourced Wikipedia article, which describes the symptoms of FeLV infection: Loss of appetite, poor coat condition, infections of the skin, bladder and respiratory tract, oral disease, seizures, lymphadenopathy (swollen lymph nodes), skin lesions, fatigue, fever, weight loss, stomatitis, gingivitis, litter box avoidance, pancytopenia, poor grooming, reoccurring bacterial and viral illnesses, anemia, diarrhea, jaundice. Sounds familiar, doesnt it? Well, maybe except for litter box avoidance. Although, now that I think of it, I do try to avoid litter boxes. So Dr Wessely, are you feeling lucky? Do you want to put your money where your mouth is and have a lick from my ice cream cone? Maybe the CDC should come out with a recommendation that people diagnosed with CFS should refrain from licking their friends until further research can be conducted. Seriously, one of the most interesting parts (to me) is that some cats who are infected get sick and others don't. Wish I knew what the difference is. Maybe the ones who get sick have a sickness ideation.