Hi, this is my first post so if I break some kind of rule or seem ridiculous, please forgive me. I've been going through some stuff medically and like all of you I'm trying to understand more, the difference between you all and I is that I cheated my way through biology in High School and now I must go through the late summer of my life confused. So here's the deal..... I just read the following sentence and I really don't get what "myocardial oxygen consumption" (see quote below) means ......so if anyone can give me a clue in first grader language I'd be terribly grateful. Thanks "In this issue of Circulation,1 Zhang and coworkers provide convincing evidence that ACE inhibitors reduce myocardial oxygen consumption by preventing the degradation of bradykinin, which subsequently stimulates the release of nitric oxide (NO)."