I am sorry to create a new post everytime something helps me, but I feel it's important. I have always thought, through the course of this, "why don't people blast it from the rooftops when something helps?" So I am. So this week, on the heels of my Acai success (been taking Acai awhile, but for some reason lately it's been really clicking with me, perhaps because the stress of planning a class reunion/plane ride/trip with family is over and I can now think and sleep).....anyways, on heels of Acai success during "lack of stressful month," I started being diligent with TMG (tri methyl glycine). I have the Now brand tablets that exploded in the bottle due to humidity, but somehow I figured out a way to swallow a tab a day..... Wow! Definite energy boost, 15 minutes later. Not so much brain function, just feeling like I could walk, jog, be up! I have pep in my step. Right now, this is the theory I'm operating under..... http://planetthrive.com/2009/06/pall-noonoo-protocol/ Yes, I've been creating a lot of posts. I feel like I am finally finding things that help, and getting recent stress off my shoulders is making the successes from the supplements shine even more. I have tried many things, like many of us. I feel the TMG may even be better than Acai. I feel they are both more helpful to me than any B12 or B vitamin I've tried. So far, the most helpful B12 seems to be either Perque sublingual hydroxy or methyl B12 shots, but I've given up on depending on B's for help. They help, but not as much as other things, for me, right now. NAC seems to help me too, but to a lesser extent then Acai and TMG. Order of helpfulness: Now brand TMG, Now brand Acai capsules, Now brand NAC with hydroxy B12 perque sublinguals (taken together, they are tied for third), methyl B12 shots. This is based upon taking said supplement, and observing how much better the next few hours are. With all of the above, I "notice" a difference. If something doesn't produce anything noticable and day-altering, I don't mention it on this forum. I don't know WHY anything is happening, just trying to help others. I use iherb.com to buy everything, because I see success from their supps, so why try something from Whole Foods, etc? I am afraid to change brands/suppliers. I still have CFS. I am just feeling somewhat better. I still think my sleep is not ideal and is not leaving me refreshed. Working on that.