Review: 'Through the Shadowlands’ describes Julie Rehmeyer's ME/CFS Odyssey
I should note at the outset that this review is based on an audio version of the galleys and the epilogue from the finished work. Julie Rehmeyer sent me the final version as a PDF, but for some reason my text to voice software (Kurzweil) had issues with it. I understand that it is...
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TLR-2 and borrellia (lyme)

Discussion in 'Lyme Disease and Co-Infections' started by roxie60, Oct 25, 2014.

  1. roxie60

    roxie60 Senior Member

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    Central Illinois, USA
  2. duncan

    duncan Senior Member

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    I would interpret it the same way. I notice the publication date is 2005. It is also primarily a German endeavor, and that country hasn't been as quick as others to wholeheartedly adhere to IDSA Guidelines.

    I wonder if there were ever any follow-up studies.

    Incidentally, you would think the NIH would be following this lead, or even something similar, considering its principal, if not sole, focus these days is diagnostics.
     
    Last edited: Oct 26, 2014
  3. Valentijn

    Valentijn The Diabolic Logic

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  4. duncan

    duncan Senior Member

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    rsID? Boy, do I feel ignorant... This is gene talk? I can almost guarantee the NIH isn't looking at this relative to Lyme patients. :)
     
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  5. Valentijn

    Valentijn The Diabolic Logic

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    It's been researched a fair bit regarding other infections, and it sounds like variations elsewhere in the gene often have a very significant impact.

    23andMe data for the rest of the gene looks very normal for 31 patients I have full data for, when compared to 31 controls. One possible exception is rs3804100 where we have 2 patients and 0 controls who are homozygous for the rare version. The usual homozygous prevalence is 1.2%, but we're at 6.5%. It could just be a fluke though, since it's pretty small sample size.
     
  6. duncan

    duncan Senior Member

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    "23andMe data for the rest...looks very normal for 31 patients..." Lyme patients?
     
  7. Valentijn

    Valentijn The Diabolic Logic

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    ME patients from this forum.
     
  8. duncan

    duncan Senior Member

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    Understood. Thanks.
     

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