They have made only a few statements on XMRV (which is one reason I questioned Koan's choice of the word repeatedly - they have not done that much). I thought Dr. Vernon's statement 'XPlained' was well done; she stated XMRV could be the game changer that we've been waiting for while highlighting the need for replication and more information. The CAA asked for an official statement from the National Cancer Institute on XMRV - good for them - nobody else thought to do that. The CAA listed the prostate study as the example of what can go wrong when different studies used different techniques. In light of that they said they were working to try to ensure that other studies use the same subset of patients to replicate the WPI study. This is a problem because the CDC very likely doesn't have the information to ensure that those types of patients are being tested. Too careful? - I don't see a pattern of trying to discredit this research. I see an organization being careful - once again, probably being too careful for most patients tastes - something has hurt them in the past and will probably hurt them now. They're obviously not being cheerleaders but if you look at other statements from prominent support groups in the UK I think you'll find similar statements. C- I certainly wouldn't give them an F. I would probably give them a C-because they have not stepped forward in several ways. They are not, for instance, a real information source on XMRV - which they should be; they should have several sections on their website discussing all the different aspects of XMRV. In that sense they're not relevant in a way they really should be. That continues to be a real problem for them. They are not necessarily the place to go for information. (That said none of the support groups either here or in the UK are - for XMRV - none of the organizations really picked up the ball. The IACFS/ME didn't even issue a statement for almost 2 weeks and then it was very paltry). I would characterize them as being more than a bystander that's for sure but as the central source that they should be - no.