Soxan.. i hope you push for a biopsy. As another said, thyriod cancer is VERY COMMON in our illness. Ive heard of some CFS/ME specialists finding it in their patients at a rate of 17%. (I think i recently heard of one finding it at higher rates then that). You need to make sure this is completely ruled out. ...... I cant remember who it was but someone here mentioned weight gain for no reason and cholestrol going up and food issues. Make sure you've been tested for insulin resistance if those things are going on by a 2 hr insulin tolerance test. Those symptoms are what my insulin issues have caused (Ive been putting on weight from what it appears to be from drinking cordial, due to insulin issues). The kind of weight gain which goes onto the tummy.