Although my own interests the XMVR virus relate to CFS/ME, my daughter has been struggling for 7 long years, all of her teens, with disabling Fibromyalgia. Her pain levels have developed into ungodly, intractable, soul braking levels. I wanted to share what a very sharp, thoughtful pediatrician said about how a neuro-virus like XMVR might produce this kind of central pain syndrome. A number of Fibro people, not to mention CFS/ME folks, develop this over time. He makes a link I've not heard spoken of so clearly elsewhere. He said: "The recent discovery of a rather striking correlation with a gamma retrovirus, XMRV, also raises concern that the pain seen in fibromyalgia may not be related to a only a problem with the CNS management of affect, but reflect a true neuropathic pain, like that seen in conditions that afflict the CNS. Not to be too shocking, but the example of rabies comes to mind. A viral infection that has nothing to do with mood per se, causes cellular inflammation in the brain that leads to quite agonizing pain. Could XMRV do something similar? We do not yet know."Please note that this quote is out of a larger context email he is addressing and he is not at all ascribing FMS merely to affective dysregulation.