A New Decade of ME Research: The 11th Invest in ME International ME Conference 2016
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Thorne B complex

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Jodie28, Jan 31, 2015.

  1. Jodie28

    Jodie28

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    Hello,

    I have a question about the Thorne Basic Bcomplex. The one I have used untill now has Ca-5-methyltetrahydrofolate. I wanted to order new Thorne Basic Bcomplex, but now it says 5 MTHF (quatrefolic) on the bottle. Is this both the same ingredient, but just another name?

    Thank you very much for your answers

    Greetings, Jodie
     
  2. mgk

    mgk Senior Member

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    Technically, they're not the same, but should have comparable efficacy. If you're really sensitive to the amount of folate, you may notice a difference, but really the differences are more technical than practical.

    Just for completeness, here's the technical part. Ca-5-methyltetrahydrofolate or Metafolin is the calcium salt of levomefolic acid (the thing we care about), whereas Quatrefolic is the glucosamine salt. So they both contain the same substance, just bound to a different carrier.
     
    Last edited: Jan 31, 2015
  3. August59

    August59 Daughters High School Graduation

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    Upstate SC, USA
    Just curious! - I thought I had read somewhere that unless "L" or "6S" in the label that it is the racemic version and contains both the "6S" (active) and the "6R" (inactive) isomers. I'm not sure if side effects or absorption issues are associated with the "6R" isomer or not.

    Maybe someone can answer this???

    I would be a little surprised if "Thorne" used what might be considered as a less active product though!
     
  4. mgk

    mgk Senior Member

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    Thank you, you're right, I should have been more careful about that. The "L" or "6S" is crucial. I can't seem to find a picture of the old bottle, but I'm guessing it says Ca-L-5-methyltetrahydrofolate. If it's Ca-5 then some portion of it could be inactive like you said.

    Quatrefolic is a brand name for "L-5-Methyltetrahydrofolic Acid, Glucosamine Salt", so if it says Quatrefolic, you're good to go. Similar thing for Metafolin.

    There's a lot more information here: http://mthfr.net/l-methylfolate-methylfolate-5-mthf/2012/04/05/
     
    Last edited: Feb 1, 2015
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  5. TheWig

    TheWig

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    Quatrefolic is :thumbsup: [6S]-5-Methyltetrahydrofolic Acid Glucosamine Salt.
     
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