I'm in my third day on Valcyte, 900mg 2x/day. So far the side effects are manageable. All day yesterday I had chills that felt like a fever, but my temp wasn't high. Feel like there's a mild electric current pulsing through every nerve in my body -- I had that when I started acyclovir also. Also have had roaring sound in my ears when I lie down. Today body aches are pretty bad, but I can handle. Was expecting to be very tired, but I actually have been so agitated that I'm having more trouble sleeping. All in all, things going well.