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Things that Raise/Homocysteien

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by rydra_wong, Feb 24, 2012.

  1. rydra_wong

    rydra_wong Guest

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    I just ran across another study showing that comething in coffee and tea raise homocysteine (translate dysregulate your methylation: http://www.ajcn.org/content/73/3/532.short

    I thought I would invite comment. On a former memory stick that was stolen I had gathered some studies on coffee and tea regarding methylation and it seemed to show that coffee raises homocysteine but tea (overall) decreases it, although when tested by component, there are component(s) in tea that raise it.
    However I found studies that showed tea causes neural tube defects in pregnant woman and that showed the reason it is stronger than any chemo on the market is because it breaks folate metabolism (something I do not want). I used to drink a lot of tea and stopped for this very reason. Tea has me puzzled because so many healthy people drink it and tout its health benefits.

    On WrongDiagnosis a list of things that affect methylation was posted. I thought I'd repost here and see if anyone has any more to add.

    These food items could be a reason for crashes and the like so it seems a good idea to keep them in mind:

    Oh, I could not find that list so I guess I'll start a new one:

    Things that raise homocysteine:

    The drugs are from these two websites:
    http://www.drmirkin.com/heart/1042.html
    http://www.lef.org/magazine/mag2009/aug2009_Is-Homocysteine-Making-You-Sick_02.htm

    Azaribine
    Caffeine
    Cholestyramine
    Colestipol
    Colchicine
    Fenofibrate
    Levadopa
    Metformin
    Methotrexate
    Niacin
    Nitrous oxide
    Non-steroidal anti-inflammatory drugs (NSAIDs)
    Pemetrexed
    Phenytoin
    Pyrimethamine
    Sulfasalazine

    tea - http://jn.nutrition.org/content/137/1/223S.short (DNA hypomethylation)
    [Tea drinking (green or black) significantly lowers breast cancer rates (40-60%) in COMT+/+ and COMT+/+ but not in COMT-/- - due to catechol-containing poly[henols using up SAMe (so cancer cant grow but neither can you?) - http://cancerres.aacrjournals.org/content/63/21/7526.full ]
    insulin - http://www.ncbi.nlm.nih.gov/pubmed/10470367
    reduced kidney function - http://care.diabetesjournals.org/content/24/3/533.short
    smoke
    red wine, liquor, but not beer - http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)74186-6/fulltext
    red wine, liquor, OR beer - http://alcalc.oxfordjournals.org/content/36/3/189.short
    red wine, but beer lowers - http://www.ajcn.org/content/78/2/334.full.pdf html
    Quercetin - http://www.sciencedirect.com/science/article/pii/S0009912005003073
    Catechol-containing polyphenols use up SAMe, causing DNA hypomethylation - http://jn.nutrition.org/content/137/1/223S.full





    Things that lower homocysteine:


    estrogen - http://cardiovascres.oxfordjournals.org/content/53/3/577.full.pdf html
    http://www.sciencedirect.com/science/article/pii/S0021915099003214
    http://www.ncbi.nlm.nih.gov/pubmed/17877128
    High folate foods such as spinach, broccoli and lettuce, , asparagus, fruits (bananas, melons, lemons), legumes, yeast, mushrooms, organ meat (beef liver, kidney), orange juice. http://www.mayoclinic.com/health/folate/NS_patient-folate
    Vegetables and Citrus (diets high in folate) - http://jn.nutrition.org/content/129/6/1135.short
    soy foods - http://www.ajcn.org/content/76/2/365.short
    Not soy - http://jn.nutrition.org/content/136/1/100.short
    Honey - http://online.liebertpub.com/doi/abs/10.1089/109662004322984789
    Beer (even nonalcoholic) due to polyphenol content - http://pubs.acs.org/doi/abs/10.1021/jf048146v
    Oleuropein (Olive Leaf Extract, extra virgin olive oil) - http://jn.nutrition.org/content/138/1/36.short


    sorry - I ran out of time...
  2. greenshots

    greenshots Senior Member

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    California
    I appreciate this list since I know our Homocysteine levels have been intermittently high too.
    Thanks, Rydra!
    Angela

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