Quite a few threads have prompted me to chime in, including one on the liver/gall bladder flush, one about a 'proven' treatment/cure for Chronic EBV, one about detoxification, and one about KDM. Among others. I have a number of Mayo-diagnosed Cytochrome P450 defects and a Mayo-diagnosed MTHFR defect. Like millions of people I have problems with detoxification of both exogenous (from outside the body) and endogenous (from within the body) substances. Which really calls into question the whole "the liver is a perfectly adequate filter" concept. It may be for some. It isn't for others. I've suffered numerous adverse reactions to prescription meds (and vaccines), each more serious than the last -- the last one nearly fatal (DRESS Syndrome). This has been attributed to my body's defective detox mechanisms, finally diagnosed when I was in my sixth decade, because I pressed and pressed and pressed for answers (beyond 'You just haven't been lucky' (Yes: literally)). Our bodies were NOT 'designed' or 'evolved' to deal with the onslaught of chemicals that began merely a blink of an eye ago. Not in evolutionary terms. What if I've been on -- literally -- hundreds of courses of almost innumerable prescription meds in my more than 50 years on this planet and my detoxification systems are faulty ? Biochemically, what happens to me ... as compared to a healthy person with normal detoxification mechanisms who has rarely taken a pill ? My wife is a Nurse Practitioner. She practices Western medicine. I'm not philosophically opposed to Western medicine (at all), and I truly admire my wife and her work. She knows that Western medicine doesn't have all the answers. She's acutely aware of what you can and cannot say with certainty based on the results of a Randomized Controlled Clinical Trial (RCCT). She knows that sample sizes are the best way we currently have to TRY to account for infinitely variable individual human physiology, but that it still doesn't even come close to doing that. She also knows that the US has hundreds of thousands of "iatrogenic" (caused by medical treatment) deaths per year. One example of the limitations of the RCCT: nobody can yet say for sure whether the drug in the trial cured or killed specific people. The RCCT only tells you whether the treatment group's results, in aggregate, were better than the placebo group's aggregated results to a degree that's unlikely to be coincidence. I think that we need all possible tools available to us. I also agree that agendas play a large role in the business of medicine. That's another weakness of the gold standard RCCT: what does, and what does not, get funded and studied. In my state, physicians have consistently been fighting to legislate reduced scope-of-practice for Physician Assistants and Nurse Practitioners. They scream and yell about how dangerous it is for these mid-levels, for example, to treat children of less than a certain age. "FOR GOD'S SAKE, THINK OF THE CHILDREN !!" But there's absolutely zero evidence that NPs and PAs aren't perfectly competent to treat young kids. It's a turf war ... about money. On this forum I'm constantly amazed, astounded, and impressed at how far outside of the mainstream so many PR members are going in an effort to regain their health. They're Science Projects With a Sample Size of One, using their own best efforts to synthesize a ton of knowledge, and then taking totally unquantifiable risks by "biohacking" in endless ways. But -- happily -- I rarely see anybody chastise, deride, and lecture them. Because most of us really don't have any other better options. We do need all possible tools available to us. The episodic dogmatism (bordering -- or maybe not bordering -- on religious zeal) on this topic (by just a handful of people or so), IMHO, is really not productive, and is my very least favorite part of this otherwise incredible forum. There's an old philosophy for people who go to the gym: unless you're awfully sure that what a person is about to do is going to hurt them ... don't correct other people's workout styles. Sometimes I wonder if we shouldn't move toward that kind of philosophy on this site. "There are more things in heaven and Earth than are dreamt of in your philosophy" --Shakespeare Just one man's opinion. Your mileage may vary. Closed course. Professional driver. Don't try this at home. No animals were harmed during the making of this film. Etc., etc.