The 12th Invest in ME Conference, Part 1
OverTheHills presents the first article in a series of three about the recent 12th Invest In ME international Conference (IIMEC12) in London.
Discuss the article on the Forums.

The Strange Cases of ME Remissions Induced by SSRIs (Dr James / Dr Smith / Dr Le Fanu)

Discussion in 'Alternative Therapies' started by Jesse2233, Jul 26, 2017.

  1. eric_gladiator

    eric_gladiator Senior Member

    Messages:
    149
    Likes:
    98
    @Learner1 @JES @ebethc


    I agree with what he says. In my also caused a permanent damage that I do not know how to improve, before this everything was easier but let me be guided by an incompetent doctor who supposedly compared my illness to his psoriasis. At the moment I think it will happen. By the way, what do you think of the ldn? Is there a risk of relapse or something?
     
  2. Learner1

    Learner1 Professional Patient

    Messages:
    1,200
    Likes:
    1,993
    Pacific Northwest
    There are repair mechanisms for mitochondria. They also die off and are recycled every 6-8 weeks or so. At the conference the researchers said if you have more good ones than bad ones, you should still be ok, til you reach a tipping point, especially if your mtDNA are damaged.

    The important thing is to stop anything that is damaging them and do things that encourage healthy ones. Naviaux's list of cell dangers is a good list of things to avoid. So are psychiatric drugs as noted in the links I provided.

    Folate, B12, B6, amino acids and lipids like phosphatidyl choline and NT Factor are useful nutrients. And working on making new food ones - PQQ and careful exercise can help.
     
    ebethc likes this.
  3. JES

    JES Senior Member

    Messages:
    465
    Likes:
    742
    There is no permanent damage of mitochondria in CFS/ME. It might be that a drug you used damaged the mitochondria, although I find it unlikely, but then as poster above said, mitochondria are recycled every 6-8 weeks.

    But anyway, CFS/ME is not mitochondria being permanently damaged, if they were as in mitochondrial diseases, you would most likely die or end up in a state where no remission is possible. But we know CFS/ME patients have reported "temporary" remissions from many different things and remissions that happened within days. Regarding LDN, I consider it one of the safest medications, mainly because Naltrexone has been FDA approved at dosage of 50 mg, and the LDN dosage is 10 times smaller.
     
    ebethc likes this.
  4. eric_gladiator

    eric_gladiator Senior Member

    Messages:
    149
    Likes:
    98
    @Learner1 @JES


    There are people whose symptoms got much worse with an antidepressant, something has to do ad to cause that or then I can not find an explanation. to me it happened to me, I had been wrong for a long time but I had a more or less normal life until I tried duloxetine and I came literally round and with a number of symptoms that I totally ignored.
     
  5. Learner1

    Learner1 Professional Patient

    Messages:
    1,200
    Likes:
    1,993
    Pacific Northwest
    I agree. I watched a family member go through 9 psychiatric drugs which did little to help, but caused worsening if symptoms and suicidal impulses.

    Many antidepressants sap the body of nutrients, like folate, glutathione, etc. and cause damage to mitochondria, which can definitely worsen symptoms.

    When we finally took a nutritional approach with a functional medicine doctor, and replenished missing nutrients, the symptoms went away completely and the drugs were not needed. It took awhile as bottlenecks are cleared, then we found the next problems, at. so it was an iterative process over several months.

    B vitamins, like B12, folate, and B6, amino acids, like tyrosine, tryptophan, GABA, glycine, cysteine, and taurine, antioxidants, like ALA, vitamin C and glutathione, minerals like zinc, selenium, and iodine, and lipids like DHA/EPA, flax seed oil, phosphatidyl serine and choline can all be useful in improving brain symptoms.

    It is worthwhile to test and figure out deficiencies, though, rather than randomly throwing nutrients st the problem, which could lead to unintended consequences.

    And once you know the dynamics, its easy to adjust when symptoms arise. My chemistry has been manipulated and occasionally gets out of whack, but all I need typically is a little folate, B12, methionine, or TMG to make symptoms go away.

    Good luck in finding alternatives to the drugs...
     
    ebethc and Jesse2233 like this.
  6. eric_gladiator

    eric_gladiator Senior Member

    Messages:
    149
    Likes:
    98
    @Learner1

    my analyzes in general go well. How would you know if you have deficiencies? The analysis of the immune system is valid for this?
     
  7. Learner1

    Learner1 Professional Patient

    Messages:
    1,200
    Likes:
    1,993
    Pacific Northwest

See more popular forum discussions.

Share This Page