You are most welcome. I tossed that in there since 99% of the posters get that distinction wrong and think folates in vegetables are either folinic or folic acid. Similar in some ways but different in other key ways. I still wonder if the health of ones intestinal lumen has something to do with how vegetable folates factor into various problems. I only say this since I have Celiac's so my intestines are not in good shape since it took me 40 years to determine the Celiac's. Uggh. Charlie horses are almost universally an potassium electrolyte problem. B12 will not by itself drive the potassium need. I know this from personal experience. It is the combination of methylfolate and meb12 and of course addtional methylation support only drives the need harder. Supposedly these are startup symptoms but I stop calling something startup after several months. Low potassium in the intracellular space will cause muscles to ache. But not quite sure what you mean about down in the bones. I will say that muscle pain down in the feet and lower legs is ALWAYS a sign of low potassium for me and my brother. It is my main clinical barometer of my potassium status. Then again not that I think of it the feet have so many bones in them and so many muscles that it does kind of feel like bone ache when it gets bad. But you are getting this with methyl b12 alone? Curious.