A study showing the role of LPS in Lyme disease. http://www.ncbi.nlm.nih.gov/pubmed/3577475 Borrelia burgdorferi lipopolysaccharide and its role in the pathogenesis of Lyme disease. A study showing the role of LPS in copper issues. http://www.ncbi.nlm.nih.gov/pubmed/23780468 The alteration of copper homeostasis in inflammation induced by lipopolysaccharides. I am trying to understand Lyme disease and it's relationship to metal handling, metal supplementing, metal deficiency, and ability to bring about healing through this knowledge.