With Silvermans retraction of his sequences from the Lombardi 2009 Science paper, the people running the 0/0 studies have huge problems. The VP-62 sequence is now known not to correspond to the gammaretroviruses detected by Lombardi et al. It is also known that Silverman's primers are capable of detecting the VP-62 plasmid and NOT capable of detecting the gammaretroviruses which exist in the Lombardi CFS patients. The WPI and NCI tried to use Silverman's primers on the patients who tested positive for their nested PCRs, but could detect nothing. A great number of the 0/0 studies used Silverman's primers alone or in combination and thus their negative findings are invalid. The slide being so viciously attacked demonstrates that the viruses are normally in a latent state which is maintained by methylation of the provirus. If one removes the methyl groups as shown by the experiment in the slide and the virus becomes active. So what, says a chorus of voices - well, the virus or viruses are integrated into G-C rich areas called CpG islands. These are extremely difficult if not impossible to amplify using standard PCR approaches. Any PCR which has been adjusted to detect the VP-62 clone in a spiked sample would not have a prayer of detecting a human MLV related gammaretrovirus integrated into such a region even if the virus did have the same sequence as VP-62 which it or they do not. Thus the combination of Silvermans retraction and the discovery that demethylation can activate the virus or viruses in question completely invalidates ALL the negative 0/0 studies Stoye, Coffin and ERV and their ilk must get Lombardi retracted at all costs before the scientific community as a whole realize that.