Another question I have regarding biomarkers - I'm going to the Pacific Fatigue Lab at the end of January for the same reason as everybody else, to support my disability claim. I'm pretty sure it won't do me any permanent damage, though I expect the aftermath won't be pretty. It would be interesting to know if any of the proposed biomarkers will be able to differentiate the *degree of disability* in PWCs without the need for an exercise test. Just a test giving a yes or no on whether I have "true" CFS would probably not be enough to demonstrate that I am disabled from it, since lots of PWCs aren't fully disabled. And of course the SSDI sets a very high standard for needing to prove you are *totally* disabled from doing *any* kind of work.