I am wondering if there is a split between people who experience muscle 'fatigue' vs muscle 'weakness'. Here is my understanding of the difference between the two: Muscle fatigue - associated with pain, burning sensation, muscle cramping or other bothersome symptoms. With muscle fatigue you can generally move the muscle if you have to - you just really don't want to. Muscle weakness - in some disorders is often not associated with pain or other symptoms - there is simply an inability to move the muscle. Which do you experience after activity? The poll will look at a variety of different muscle states.