1. Patients launch $1.27 million crowdfunding campaign for ME/CFS gut microbiome study.
    Check out the website, Facebook and Twitter. Join in donate and spread the word!
Knitting Equals Pleasure, Despite ME/CFS
Jody Smith loves knitting. Again. She thought her days of knitting and purling were long over but ... she's back ...
Discuss the article on the Forums.

The Human Microbiome & Acquired Mitochondrial Disease

Discussion in 'General ME/CFS Discussion' started by Radio, Feb 24, 2014.

  1. Radio

    Radio *****

    Messages:
    453
    Likes:
    249
    Gut bugs misbehaving?
    http://phoenixrising.me/archives/20926





    The gut flora as a forgotten organ
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500832/
    Resistant starch
    http://en.wikipedia.org/wiki/Resistant_starch
    The Resistant Starch Challenge
    http://forums.phoenixrising.me/inde...ge-is-it-the-key-weve-been-looking-for.26976/


    http://www.aspirenaturalhealth.com/...e-puzzle-post-149-by-dr-tim-gerstmar-3262012/

    http://www.drmyhill.co.uk/wiki/Fermentation_in_the_gut_and_CFS

    http://www.naturopathydigest.com/archives/2006/jun/vasquez.php

    Disclaimer
    The information on this thread is not intended to be medical advice. The information is meant to inspire and motivate you to make your own decisions surrounding your health care and dietary needs. It is intended for educational and informational purposes only. You should not rely upon any information found on this thread to determine dietary changes, a medical diagnosis or course of treatment. Readers should perform their own research and make decisions in partnership with their own health care providers. Any statements or claims about the possible health benefits obtained from any foods or supplements mentioned on this thread have not been evaluated by the Food & Drug Administration and are not intended to diagnose, treat, cure or prevent any disease.


    Contribution of dietary protein to sulfide production in the large intestine http://ajcn.nutrition.org/content/72/6/1488.full

    Sulfate-reducing bacteria
    http://en.wikipedia.org/wiki/Sulfate-reducing_bacteria
    Last edited by a moderator: Feb 28, 2014
    Asklipia likes this.
  2. Radio

    Radio *****

    Messages:
    453
    Likes:
    249
    http://www.dr-forsyth.com/Dr_Charles_Forsyth/Gastrointestinal_Investigations.html

    Please read this thread for more treatment options and texts references.

    Poisoning-the-Mitochondria-part-2
    http://forums.phoenixrising.me/index.php?threads/poisoning-the-mitochondria-part-2.28325/

    Last edited: Mar 1, 2014
  3. Radio

    Radio *****

    Messages:
    453
    Likes:
    249
    Last edited: Mar 4, 2014
    Crux likes this.
  4. Radio

    Radio *****

    Messages:
    453
    Likes:
    249
  5. Hip

    Hip Senior Member

    Messages:
    3,002
    Likes:
    2,851
    I tend to feel better when there is more hydrogen sulfide in my intestines (as measured by odorous flatulence), as a result of eating hydrogen sulfide producing foods. I feel calmer and more relaxed, and in a good mood.

    This may be because hydrogen sulfide has antidepressant and anti-anxiety effects, and this study indicates:

    Antidepressant-like and anxiolytic-like effects of hydrogen sulfide in behavioral models of depression and anxiety

    So in my case, I perhaps should be trying to increase the production of hydrogen sulfide in my gut.

    Does anyone have any suggestions on how to increase gut hydrogen sulfide, by the way? I find that it is beans that produces the most flatus odor, and so perhaps the most hydrogen sulfide (though I understand that methyl mercaptan is the other odorous gas produced in the intestines). However, I am currently on a bean and nightshade free diet.

    The species of bacteria I have in my gut (according to my Genova Diagnostics stool test) are:

    Proteus mirabilis
    Staphylococcus aureus
    hemolytic Escherichia coli
    alpha hemolytic Streptococcus
    gamma hemolytic Streptococcus
  6. Radio

    Radio *****

    Messages:
    453
    Likes:
    249
    Hello Hip,

    People who have genetic polymorphisms and methylation issues tend to generate to much H2S. Dysbiosis is one of the critical factors in the chain of disease. Hydrogen sulfide is an inhibitor of cytochrome oxidase at the end of the mitochondrial respiratory chain. Streptococcus, Enterococcus and Prevotella, can turn sulfur into hydrogen sulfide gas, as well as eating a diet high in animal protein. Hydrogen sulfide gas is toxic to our nervous systems and our mitochondria. Anything that can potentially inhibit ATP is a problem that needs to be avoided in my opinion. Low H2S levels can be beneficial in healthy individuals with normal detoxification metabolisms.
    Last edited: Feb 28, 2014
  7. Hip

    Hip Senior Member

    Messages:
    3,002
    Likes:
    2,851
    This is an interesting article that provides useful info about hydrogen sulfide in the body:

    Hydrogen sulfide-releasing anti-inflammatory drugs
    John L. Wallace, Inflammation Research Network, University of Calgary

    This excerpt is of interest:
    So you would have to have quite high levels of hydrogen sulfide in the gut to overcome the body's efficient H2S scavenging systems.
  8. Radio

    Radio *****

    Messages:
    453
    Likes:
    249

    Metabolic Imbalance + Dysbiosis + Methylation Dysregulation + Chronic Deficiencies + Environmental Factors = Acquired Mitochondrial Damage.



    Metabolic syndrome and mitochondrial function: molecular replacement and antioxidant supplements to prevent membrane peroxidation and restore mitochondrial function.
    http://www.ncbi.nlm.nih.gov/pubmed/17243117

    Redox metabolism abnormalities in autistic children associated with mitochondrial disease

    http://www.nature.com/tp/journal/v3/n6/full/tp201351a.html
    Last edited: Mar 4, 2014
    Christopher likes this.
  9. Radio

    Radio *****

    Messages:
    453
    Likes:
    249
    Cytochrome c oxidase
    http://en.wikipedia.org/wiki/Cytochrome_c_oxidase
    http://lpi.oregonstate.edu/infocenter/minerals/copper/

    Hydrogen sulfide wikipedia.org/wiki/Hydrogen_sulfide

    Histotoxic Hypoxia
    http://en.wikipedia.org/wiki/Histotoxic_hypoxia

    Oxidative phosphorylation
    http://en.wikipedia.org/wiki/Oxidative_phosphorylation

    Note by SOC: I added quotation boxes to this post and moved the reference to below the text with which they are associated.
    Last edited: Mar 7, 2014
  10. Christopher

    Christopher Senior Member

    Messages:
    457
    Likes:
    169
    Pennsylvania
    A lot of this makes sense, thanks @Radio
    Last edited by a moderator: Mar 1, 2014
    Jon_Tradicionali and Radio like this.
  11. Kina

    Kina Moderation Team Lead

    Messages:
    5,536
    Likes:
    4,077
    Ontario, Canada
    Moderator Message:

    Just to let you know, I have removed quite a few posts from this thread mostly because a problem has been corrected so the posts no longer apply. The thread is now back on course. The posts I have removed were not rule breaches. I usually contact members individually to let them know if I have edited/removed posts. I am just posting this here to save time.

    Carry on.


    Kina :)
    Radio and Aileen like this.
  12. Christopher

    Christopher Senior Member

    Messages:
    457
    Likes:
    169
    Pennsylvania
    What happens when you eat high sulfur foods?
  13. Hip

    Hip Senior Member

    Messages:
    3,002
    Likes:
    2,851
    Nothing out of the norm in the case of high sulfur foods.
  14. kangaSue

    kangaSue

    Messages:
    30
    Likes:
    31
    Australia
    Garlic appears to be a good source to increase hydrogen sulfide.
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2084282/
  15. kangaSue

    kangaSue

    Messages:
    30
    Likes:
    31
    Australia

See more popular forum discussions.

Share This Page