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The Glutamate Blocker Namenda

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by slayadragon, Jun 21, 2010.

  1. adreno

    adreno 3% neanderthal

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    Nope, haven't tried them. Not eager to, either. But I conclude that high glutamate is not a big problem for me.
    heapsreal likes this.
  2. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    Theres also dextromethorphan/dxm that an nmda antagonist which is used by some to prevent benzo and stimulant tolerance and have read it helps withdrawal.

    I mainly take zolpidem or zopiclone with maybe valium or anthistamine. On a dosage equivalent I dont use more than 10mg. I go through crappy sleep cycles unsure if it benzo tolerance or just one of those things. Normally I try to take a few days break from benzos and take dxm nightly for a few weeks at the dose recommended on the bottle. Then I go back to my usual dose.

    Whats intrigued me was how quickly the brain fog went which I always seem to get in the afternoon. Looking into how memantine works then it possible attacks my issues from several angles. Also neuroprotective and may help reverse neurological damage we have, thats my assumption.

    I think everyone will respond differently but its good to hear from others experiences??
    Mudhole likes this.
  3. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    I thought It interesting when I read it can help with inflammatory cytokines such as tnf alpha. I have also been looking into ways to increase dopamine which this seems like it does. The different mechanisms im finding interesting.
  4. adreno

    adreno 3% neanderthal

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    I find magnesium threonate and NAC quite effective for NMDA antagonism/modulation. Memantine is more than an NMDA antagonist.
    heapsreal likes this.
  5. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    yes, i think im getting its anti inflammatory effects on cytokines like tnf but thats just a hunch as well as a dopamine boost.
  6. minkeygirl

    minkeygirl Senior Member

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    My doc just recommended the magnesium threonate instead of LDN.
    Little Bluestem likes this.
  7. Psydrob

    Psydrob

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    I was prescribed Namenda off label for severe migraines at a low dose. I started with one 7.5 mg xr capsule and worked up to 3 of these capsules. It prevented and was a rescue med for migraines as well when I began using 2 capsules. Three put me in a stupor when it interacted with other meds; amitriptyline, baclofen and tramadol. I was weaning myself off tramadol and went cold turkey and found that i didnt feel the intense pain after 1 month of 2-3 namenda a day. I do believe my body is going thru withdrawal from tramadol as the anxiety and overpowering fatigue has been present since i went cold turkey with tramadol. It has been 14 days since my last 100 mg xr tramadol pill. One day was very bad as far as agitation and anxiety but to be off prescription pain meds for me is a miracle.

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