YO SPIT, Sorry to shout. Just wanted you to see me. Check out fig 1 in Wessely -- the positive control. Is that shome faint stuff or what? If the + control is that faint, what would a positive from a human sample look like (if there was one)? If anything, the + control should be easier to detect than a patient sample. First of all, XMRV is surely 1000x or so more concentrated in some plasmid, per total amount of DNA, than it is in some human genome, non? Have ye any further thoughts on sensitivity when one is XMRV-spiked water as opposed to human DNA extracted from whole blood?