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The Daily Beast: The cure for brain diseases is in your gut

Discussion in 'Other Health News and Research' started by Sasha, Apr 30, 2015.

  1. Sasha

    Sasha Fine, thank you

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  2. Sasha

    Sasha Fine, thank you

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    Just realised the article is by Daniel Perlmutter, who has a new book out ('Brain Maker') on this issue.
     
  3. Sidereal

    Sidereal Senior Member

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  4. adreno

    adreno PR activist

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    Right on.
     
  5. Sidereal

    Sidereal Senior Member

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    There will come a time when people dissing the microbiome will look as ridiculous as the people who opposed the germ theory of disease.
     
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  6. Sasha

    Sasha Fine, thank you

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    I hadn't even been aware that the 'leaky gut' stuff was viewed as respectable.

    So hard to know what's considered established and what's not.
     
    aimossy likes this.
  7. aimossy

    aimossy Senior Member

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    Leaky gut is being mentioned more and more by mainstream researchers. I have also heard that there is some really hot stuff coming out, dont know when. Basically regarding Parkinson's and the ENS - with respect to dopamine and it being all kicked off by a virus. Only time will tell if this rumor actually gets to print though.
     
    Last edited: Apr 30, 2015
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  8. Sasha

    Sasha Fine, thank you

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    ENS?
     
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  9. dannybex

    dannybex Senior Member

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    You're smarter than I am by far, but it's my understanding that those who opposed the germ theory basically said that germs can only take advantage of the host if the 'terrain' is weakened or stressed in some way. So couldn't that be applied to the microbiome -- that germs can take over only if the microbiome is imbalanced or stressed?
     
  10. Sidereal

    Sidereal Senior Member

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    You are grossly overestimating my intelligence sir but to try to answer your question, some objected to any such concept as microscopic germs while others made more nuanced arguments. I do think you have to ask yourself what constitutes the terrain and what shapes it to become what it is. I believe our microbiome is crucial in shaping the terrain, particularly the immune and autonomic nervous system. Thus, if your beneficial commensals have been decimated it's easy for any pathogens to take over and produce a subjective experience of infection even though it's not a real infection in the traditional sense of the word... more like a gradient of dysbiosis.
     
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  11. Antares in NYC

    Antares in NYC Senior Member

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    Love the article, but hate the Daily Beast. It's a click-bait hole that has published extremely nasty articles on Lyme patients in the past.
     
  12. Antares in NYC

    Antares in NYC Senior Member

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    Two years ago I had a respectable gastroenterologist laugh in my face when I mentioned "leaky gut."
    He also missed an obvious diagnosis on a colonoscopy, and mistook electronic noise for something else, giving me a major scare.
    (This year I saw a different gastro, who was the polar opposite and was able to make the right diagnosis.)
     
    Last edited: Apr 30, 2015
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  13. dannybex

    dannybex Senior Member

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    Thanks for the clarification. I share your viewpoint. Makes complete sense.
     
  14. MCRobbie

    MCRobbie Senior Member

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    If many diseases do begin in the gut or are impacted by a derangement within the gut I think its going to be difficult to turn that derangement towards health in illnesses like ME/CFS or in disease states where someone has been sick for many years due to this derangement.

    The gut is spectacularly complex and mine has been in a state of profound dysfunction for over twenty years now likely due to a complex of factors, fifty plus course of antibiotics which can do terrible damage to ones biome, poor nutrition in my youth, not being breast fed, and who knows what else of a hundred other different factors.

    Ive found it impossible to turn my gut towards health and I have tried just about everything, every diet, FODMap, Gaps, extremely high prebiotic fiber, low fiber, low histamine, ketogenic, fasting, probiotics, fermented foods, raw milk and colostrum, every natural anti microbial, natural anti inflammatory, FMT's, and the list goes on. Its rather remarkable that I haven't been able to turn it though others do have success. But once the gut becomes deranged and imbalanced with a dysfunctional mix of bacteria, viruses parasites, inflammation, leaky gut, in many cases it can be very hard to turn .

    There are no easy solutions.

    Right now Im on round two of FMT's and lots of Fresh liquid colostrum. Well see..........
     
    Last edited: Apr 30, 2015
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  15. 5150

    5150 Senior Member

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    You sound remarkably like I am when it comes to gut issues.
    "normally" trained GI doctors will wait until we are almost dead before they take any action.
    Pretty sure most of them are just idiots, otherwise what other reason?
    This useless one that I have seen looks at me rather oddly.
    We just have to find the good one. I feel like I need a fecal transplant.
    Are they really so stupid that they think that won't work? Question to them: what else is there to lose?
    Their inaction has already ruined me.
     
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  16. MCRobbie

    MCRobbie Senior Member

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    Ive found my greatest frustration with Drs have come when talking to gastroenterologists.
     
  17. Gingergrrl

    Gingergrrl Senior Member

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    No, @Sidereal, gotta disagree here and you are truly intelligent my friend ;)
     
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  18. aimossy

    aimossy Senior Member

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    @Sasha Enteric Nervous System (in the Gut)
     
    Sasha likes this.
  19. Wayne

    Wayne Senior Member

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  20. Sasha

    Sasha Fine, thank you

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    I must order it...

    There's an odd statement in a customer review: "Thanks for pointing that out. To clarify, I know others have written about the links between diet, gut microbes and mood. I should rewrite that sentence. However in Brain Maker Dr. Perlmutter shares new research and nutritional strategies to decrease the production of Clostridia-derived short chain fatty acids (SCFA)."

    I wonder if he mean 'increase'?
     

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