Hi, What experience/opinions do you guys have with testing relating to methylation? Based on long standing symptoms and recent methyl supplement reactions, I now suspect I am an over-methyator. Symptoms - I have an absence of seasonal allergies, high sensitivity to perfumes, high levels of internal anxiety, tendancy to overreact to things, struggle with depression, have a high empathy for others and neck/head pain. Recent experience - I got very hot and angry/aggressive on Solgar MetaFolin and to a lesser degree Methyl B12. I am calm and relaxed shortly after taking niacin (whether taking B12/Methly Folate or not). I am now taking Folinic Acid, occasionally some Folic Acid (Yes, I know!) and HydroxyB12 and do well with all of them. I would like to have some tests to see if I am a true over-methylator, because I also wonder if my symptoms and experience come from my specific snps. COMT, MAO A and and to some degree VDR Taq could be biasing my opinion to a false conclusion. I have considered testing for histamines (as a guide for methylation status), Serotonin/dopamine (for mood and drive), Cu/Zn (for irritability). What do people thing of the NutrEval test, I know it is expensive, but does appear to be very comprehensive. Many thanks for any comments or advice you may have.