Surprised this wasn't already posted: Targeting ‘Broken’ Metabolism in Immune Cells Reduces Inflammatory Disease http://www.scienceandtechnologyrese...sm-immune-cells-reduces-inflammatory-disease/ In a study published this week in the journal Nature Communications, they explain how blocking a single enzyme enabled them to reprogram macrophages – the immune cells which are activated in inflammatory conditions – to calm their activity and reduce inflammation in rats and mice with human-like disease. At the heart of the research is the Krebs cycle, a complex loop of reactions which cells use to feed on sugar and generate molecules of ATP, the universal energy currency for cells. Looks like this is decent evidence of a link between the immune system and energy issues that could be associated with ME CFS. I'm too foggy at the moment to figure it all out and comment. So tag smart people. @nandixon @Hip @Jonathan Edwards Full article: http://www.nature.com/articles/ncomms16040 Thanks in advance for anyone that can comment on this.