So 12 of us to 11 controls. 1 control hetero.. while 3 of us have some mutation of it. I wonder if the 3 of us who have some form of mutation of this, if we all have MCS? I really follow what you have done there with interest. I hope some time you can expand on what you are doing there . I really want to know how a larger groups of both would compare. ........ For anyone interested, today I came across a list of conditions found in mastocytosis and lots of them are ones found in us http://www.mastocytosis.ca/perelated.htm so maybe there is some close connection between this illnesses with some of the same pathways involved?