That's great! I felt bad that you were getting a migraine so I didn't want to argue...if it works it doesn't really matter how...but I am happy that is clear to everyone now. Thank you so much for making the effort to make sure we are all on the same page and of course for telling us about this in the first place. As far as autoimmune, I guess it depends on the type of autoimmune condition you have, whether tagamet makes it worse or better. I don't have an autoimmune conditions and am not that well versed in them. Mary, thanks for letting us know about possible depression. I also recently read that it removes zinc from your body so I am taking extra. I don't think I am going to take tagamet/cimetidine on a continual basis though, probably just a month.