Just to reiterate the warning to the guys in the forum. I was taking Tagamet and then Zantac for 3-4 years in the early 1990s for upper gastro pain and suddenly developed all the signs of the 'male menopause/viropause' which made all my existing symptoms much worse and added a few more. Testosterone tanked from 25nmol/l in 1986 to less than 10nmol/l in 1996. Cimetedine in known to produce changes, possibly irreversable, to the sertoli cells in the testes. Gynecomastia is a known side effect.