In addition to adhering to a strict sleep hygiene protocol that included turning off TV at 9pm, 3mg melatonin, and magnesium supplementation before hitting the hay at 11pm, I noticed that as soon as I started taking a small staggered dose of Cytomel for T3 issues 2x/day, my sleep became deeper than it has been in years. I still wake up @3-4x/night to pee, but I can fall back to sleep easily. Also, 4am tachychardia, heart palps, and panic attacks have completely subsided. If you have existing thyroid issues and take T4 (Synthroid/Tirosint/etc.), please make sure your doctor tests your free T3 and T4, in addition to TSH. Your body may not be converting the hormone correctly.