I am a little curious. I have ME. I have some symptoms which predominantly affect only one side of my body. Does this indicate a localised issue or some peculiarity of the immune system. For example I get keratins on my eyeballs (Thygeson's Keratopathy), very rare, cause unknown. They irritate my eyelids like grit in your eye. Mostly in my right eye. I always have an enlarged gland behind my right ear. Contrarily I get migratory joint pain, swelling, heat (ankle, knee, wrist) mostly on my left side. Pain lasts for about 24 hours in one joint then moves onto next joint. My doctor looks at me as if I am mad when I try to explain it. Does anyone have this asymmetry? Can anyone offer an explanation? My apologies if this has already been discussed. Perhaps someone could point me to thread. Cheers.