1. Patients launch $1.27 million crowdfunding campaign for ME/CFS gut microbiome study.
    Check out the website, Facebook and Twitter. Join in donate and spread the word!
Ergonomics and ME/CFS: Have You Hurt Yourself Without Knowing It?
Having a chronic illness like ME/CFS can make it hard to avoid problems that come from bad ergonomics. Jody Smith has learned some lessons the hard way ...
Discuss the article on the Forums.

Symptom List of both Over and Under Methylation?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by chilove, Jan 27, 2013.

  1. chilove

    chilove Senior Member

    Messages:
    250
    Likes:
    46
    Hello all,

    Happy New Year!

    Can anyone direct me to a good list of under and over methylation symptoms?I think it would be very helpful for me as I adjust supplement levels.

    Thanks so much!

    Audrey
  2. arx

    arx Senior Member

    Messages:
    532
    Likes:
    139
    Hey,

    Happy new year to you too!

    Personally I've always found the topic of under and over methylation to be very debatable. Whether any of it is truth or not, I don't know. But I know that Niacin helps with the over-stimulation, regarded as overmethylation. I'll share some resources I've bookmarked about this topic. Hope it helps.

    1. Overmethylation and Undermethylation: Case Study

    2. What are symptoms of over methylation?
    3. http://anabolicminds.com/forum/male-anti-aging/114485-undermethylation-overmethylation.html


    4. http://forums.phoenixrising.me/inde...hylation-and-precursers-laymans-version.1740/


    5. Quoting from "http://forums.bettermedicine.com/sh...-deficiency-is-commonly-misdiagnosed/page1195"
    Under and Over methylation symptoms and characteristics
    Here is a collection of symtoms, signs and chracteristics of overmethylators and undermethylators from several sources. A few specific items are footnoted. I found the specific interesting. The consensus as to which is what is a bit fuzzy. Some things like depression show up on both lists according to different people. Many of the symptoms on BOTH lists are active b12 and folate deficiency symptoms. As far as response to b12 and folates are concerned, I'm just including what the sources say, not what I think. The ONLY thing they are all (sources) in full agreement on is response to SAM-e.



    UNDER METHYLATORS

    Depression
    High salivary flow
    High tear flow
    Never dry eyes
    Good tolerance of cold
    Poor tolerance of heat
    Unexplained nausea
    Hyperactivity
    Frequent colds and flu
    Phobias
    Highly motivated
    Hard driving personality
    Poor pain tolerance
    Joint pain
    Joint swelling
    Joint stiffness
    Excess perspiration
    Addictive tendencies
    bipolar disorder
    OCD
    Schizophrenia
    Insomnia
    Muscle pains
    Abundant or excess saliva in mouth
    Obsessive compulsive
    Slenderness
    Do worse on b12 and folates (4)
    Shopping/gambling disorders
    Oppositional –defiant
    Seasonal depression
    Inhalant allergies
    Frequent headaches,
    Perfectionism
    Competitiveness
    Asthma
    Vasomotor rhinitis
    Allergic skin disorders
    Pruritis
    Excess stomach acid
    Fatigue
    High libido
    Sparse body hair
    Elevated absolute basophils
    Extreme internal anxiety despite outwardly calm
    Delusion thinking rather than hallucinations
    Respond well to SAM-e, methionine, avoid folic acid (1)
    Anorexia/bulimia
    Low serotonin
    Low dopamine
    Low norepinephrine
    Psychosis
    Prone to hives
    High motivation



    OVER METHYLATORS

    Elevated serotonin
    Elevated dopamine
    Elevated norepinephrine
    High religiosity
    High artistic/musical ability
    Self injury
    Auditory hallucinations
    Absence of seasonal inhalant allergies
    Frequent dry eyes
    Multitude of chemical sensitivities
    Multitude of food sensitivities
    High anxiety evident to all
    Low libido
    Obsessions but not compulsions
    Paranoia
    Auditory hallucinations
    Underachievement as child
    Heavy body hair
    Hyperactivity
    Nervous legs
    Grandiosity
    Respond well to b12 but avoid SAM-e, inositol, methionine TMG and DMG (1)
    Treatment revolves around folic acid, niacin, B12, and a high protein diet. (2)
    Depression
    Despair
    Panic attacks
    Upper body pain
    Head pain
    Nervous
    Low salivary
    Low tears
    High pain tolerance
    Low motivation
    “space cadet”
    Learning disabilities
    Intolerance to SSRI drugs
    Low perspiration


    1 http://www.dr-bob.org/babble/20030525/msgs/229704.html
    2 http://www.favoritedr.com/anxiety.html
    3 http://www.digitalnaturopath.com/cond/C446553.html
    4 http://www.latitudes.org/forums/index.php?showtopic=837




    The above list was posted by Fred, and I don't know whether he still agrees with all this.
    Anyways, I hope the information helped.
    cph13 likes this.
  3. Lotus97

    Lotus97 Senior Member

    Messages:
    2,015
    Likes:
    419
    United States
    Overstimulation can be a symptom of overmethylation.

See more popular forum discussions.

Share This Page