I'm writing on behalf of my wife who has a progressivly worse ME/CFS. She is more or less totally bedbound with "attacks" of an exhaustion that she descirbes as suicidal. Its is unbearable. It does get better if she is playing her cards right, but it seems to return for periods every day. This seems to frighten her quite a bit, a fear and anguish which in itself does not help. She is generally a very positive person, but this development seems to break her down. It has disrupted her sleep pattern which makes it harder to get some energy back in her system. She is in contact with good doctors, but they do not have any new ideas at the moment. She has gotten benzodiazepine in order to calm her down. She is also trying the "usual" ME/CFS strategies and remedies but they does not seem to stop her quite aggressive form of the illness. Does anyone have any experience with similar "suicidal" exhaustion and have any tips how to cope with it? She is in need of some hope so any positive stories would be appreciated.