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Successful treatment of periodic paralysis (channelopathy) with coenzyme Q10

Discussion in 'Other Health News and Research' started by pattismith, Dec 28, 2017.

  1. pattismith

    pattismith Senior Member

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    Acta Myol. 2016 Oct

    Successful treatment of periodic paralysis with coenzyme Q10: two case reports
    Yuwei Da,[​IMG]1 Lin Lei,1 Karin Jurkat-Rott,2 and Frank Lehmann-Horn[​IMG]3

    Abstract
    Primary periodic paralyses (PPs) are autosomal dominant ion channel disorders characterized by episodic flaccid weakness associated with variations in serum potassium level. The main prophylactic therapy of choice for PPsis carbonic anhydrase inhibitors that are not always effective. In this report, we described two PP patients who were successfully treated with coenzyme Q10. They remained asymptomatic since initiation of treatment, which may be associated with promotion of energy synthesis, anti-oxidant activity, influence of the fiber type composition and regulation of the expression of gene. To our knowledge, this is the first report of primary periodic paralyses which have been successfully treated with CoQ10. More observations need to substantiate this clinical finding in PPs.
     

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