1. Patients launch $1.27 million crowdfunding campaign for ME/CFS gut microbiome study.
    Check out the website, Facebook and Twitter. Join in donate and spread the word!
Nitric oxide and its possible implication in ME/CFS (Part 2 of 2)
Andrew Gladman explores the current and historic hypotheses relating to nitric oxide problems in ME/CFS. This second article in a 2-Part series puts nitric oxide under the microscope and explores what it is, what it does and why it is so frequently discussed in the world of ME/CFS....
Discuss the article on the Forums.

Study of possible treatment for mental fatigue in Sweden

Discussion in 'Latest ME/CFS Research' started by Anne, May 2, 2012.

  1. Anne

    Anne

    Messages:
    83
    Likes:
    50
    A new treatment study has just begun at the Gottfries Clinic in Sweden. Professor Gottfries and his colleagues are collaborating with Nobel laureate Arvid Carlsson in this study, which will examine possible effects of the substance OSU 6162 on the brain exhaustion/mental fatigue ME patients experience. The study will be double-blind and placebo controlled. Both Fukuda and ICC will be used, and patients evaluated by experienced physicians at the Gottfries Clinic.

    OSU 6162 has previously shown effects of mental fatigue in stroke patients
    http://www1.cinp-congress.org/guest/IDa5f5d874720e5c/AbstractView?ABSID=9623


    Prof Gottfries stresses that this substance wont cure ME/CFS, but might ease one of the symptoms.

    Any thoughts on this? If I understand this correctly, OSU 6162 is a dopamine regulator. Does that mean it will increase levels of dopamine in the brain?
  2. Ember

    Ember Senior Member

    Messages:
    1,728
    Likes:
    1,777
    It's interesting that, as a dopamine stabilizer, OSU6162 has shown beneficial actions in early clinical studies for patients with Parkinsons disease. It's encouraging too that it has caused a remarkable improvement in mental stamina (as evaluated by a self assessment scale on mental fatigue) following stroke.

    Thanks for posting this! It's the first study I've heard of to be using a Fukuda and ICC cohort.
  3. barbc56

    barbc56 Senior Member

    Messages:
    1,319
    Likes:
    678
    Anne O., thanks for this important thread. Sleep is such an integral part of our DD, my belief is that we should all get a quality sleep study.

    I have had several sleep issues treated by a sleep neurologist and it's helped. Didn't cure me but certainly a relatively better quality of life.

    I would love to be able to exercise 4.6 hours per week. Definitely not reflective for most of us, eh?

    Barb C.:>)

See more popular forum discussions.

Share This Page