• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To become a member, simply click the Register button at the top right.

Study finds healthy mitochondria run 10 degrees C hotter than rest of body

BeautifulDay

Senior Member
Messages
372
The study was discussed recently in an article on Phys.org titled "Do our mitochondia run at 50 degrees C?"
https://phys.org/news/2018-01-mitochondria-degrees.amp

"The authors' results appear to show that, in maintaining our body at a constant temperature of 37.5°C, mitochondria operate much like thermostatic radiators in a poorly insulated room, running at a much higher temperature than their surroundings."
....
"Specifically, the probe's fluorescence suggested that the temperature of the mitochondria in living and intact cells, themselves placed in a culture medium maintained at 38°C, is more than 10°C higher, as long as the mitochondria are functional. This elevated temperature is abolished when the mitochondria are inactivated by various means."

For those of us whose chronic fatigue is due to mitochondrial disease or dysfunction, I wonder if this explains the cold feet, normal lower body temperature, and the change in weather temperature related uptick in symptoms?