I have been on a methylation trial before, and it seemed to help. I ran out of b12 and stopped, to see if I would notice much of a change. I have been sporadically supplementing the Jarrow b complex recommended by Fredd, w/o the b12 extras. That being said, how long should I stay off the b complex if at all, before reintroducing the extra b12? Is there any interference?