I am into the first week of 2 new genetics courses. In one, Genes and the Human Condition, they talked about how the steroid hormones enter the nucleus of the cell and can increase gene expression. So methylation is not the only thing that can turn genes on. Since so many of us have problems with cortisol, I wonder if, or how, that might tie into certain genes being expressed or not. Can't help wondering if there is a connection. There was also some interesting talk about how fruit flies have many homologous (similar) genes to us. The instructor went on to say that in fruit flies (drosophila) hundreds of disease associated genes have already been identified. All of a sudden I'm a lot more interested in drosophila! We are about to get into week 2 in Useful Genetics. I'm still busy repeatedly failing the practice quiz for week 1. The week 2 topics have to do with different mutations. One thing that has been mentioned already is that some mutations cancel each other out so a single mutation does not tell the whole story. These 2 courses are proving interesting and I haven't done any supplementary reading yet or looked at the course discussion forums.