So, I was on Prednisone for a week due to an infection and not being able to breathe. I loved it. Normally, Prednisone can go south for me. I can become rageful and feel lousy. This time, I wanted to stay on it. I had more energy, no pain, etc. Alas, my CFS doc was like "NO WAY." It's stealing from Peter to pay Paul. So, he wants me on hydrocortisone. My adrenals have been tanked. For a long time. Here are my fears; I was on it back in 2009 and I was so tired on it. I couldn't even get out of bed, it was so weird. I also just felt anxious. I know, the opposite of how you are supposed to feel. I remember my heart flying on it. Years ago, back in 2002, I could take it. But, in 2009....nope. I couldn't handle it. My doc wants me on 20 mg. One in am and one around noon. Well, this is a problem because I don't wake up until around 11 am. How are all on it/taking it doing or those who took it? What times do you take it and do any of you wake up late and take it? Also, does anyone get tired on it? I took it this morning at 11 am and within 20 minutes I became really tired. All I know is, if I become as tired as I did in 2009, I will not be able to stay on it. I was a mess and anxious as all hell. I am supposed to take the next dose at 3 pm. Any thoughts on why one becomes fatigued on it?? I suppose it depends on where your adrenals are. I literally feel like I have hit a brick wall after taking it. I don't get it. I just wish I could stay on Prednisone instead.