The Call for Opposition: Challenging the P2P and IOM Processes
In our second article on how to react to the publication of the draft P2P report, Gabby Klein provides her view of why she and a large group of advocates and patients are continuing their protest of the government’s ongoing control and manipulation of our disease via their processes...
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Started Methylation with B12 only – Neuropathy is much worse

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Kontra, Feb 26, 2014.

  1. Kontra


    Hi all,

    I’ve been dealing with a number of issues for a number of years, pretty much bread and butter symptoms for this forum – hypolglycemia, chronic fatigue, dizziness, multiple chemical sensitivity, IBS and about 40 others. The most significant however which is most severe is neuropathy, which has been progressing very rapidly in about 9 months. During and before that time my blood sugar has been under good control and I’m not diabetic. Diet is very healthy, lots of meats and no issues with gluten.

    Not much I’ve tried has helped, and I’ve always known there is a liver component to my illness especially due to having MCS and occasional liver ‘aches’ and high enzymes. One thing I hadn’t tried was methylation, due to being extremely to supplements and not being able to tolerate any detox.

    I decided to add B12, ¼ of a 1mg tablet every other day starting 3 weeks ago. I take it sublingually typically in the morning under the tongue. It did and still does ‘buzz’ me a little but It’s not effecting my sleep so I’m holding at this dose. I can feel my sensitivity to chemicals has increased which suggests to me that methylation has been ‘switch on’. I’ve not even thoughts about the co-factors yet as I’m so sensitive.

    Unfortunately my neuropathy has been getting worse. I’m almost unable to type due to the numbness and cramping in my fingers. I can still walk but the numbness and tingling has been much stronger. I’ve read lots of posts and would expect some side effects to starting methylation, but on the neuropathy side of things I’ve not read that numbness can get worse. When people have neuropathy from B12 deficiency which is then replaced, often they go through pain and burning as the nerves ‘awaken’. This is not happening to me, and the opposite seems to be happening.

    Did anyone experience anything similar when starting methylation? The obvious recommendation in the short term is to stop the B12, but this will never get me anywhere with my health I feel.

    Many thanks,
  2. adreno

    adreno Learned helplessness

    You need to take methylfolate with your B12. Try 200-400 mcg for starters.
    Critterina likes this.
  3. ahmo

    ahmo Senior Member

    Northcoast NSW, Australia
    That cramping sounds like you need some magnesium and/or potassium.

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