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A Little Poisoning Along the Road to ME/CFS
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Staph vaccine to treat CFS??

Discussion in 'Latest ME/CFS Research' started by SpecialK82, May 4, 2010.

  1. Hip

    Hip Senior Member

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    Some Notes of Mercury in Vaccines

    Note that the mercury used as a preservative in vaccines is ethylmercury (aka: thiomersal, or thimerosal), which is not known to bioaccumulate, so this form of mercury this will not increase your total body load of bioaccumulated mercury.

    The reason ethylmercury is being removed from vaccines is because a lot of parents with autistic kids put pressure on governments to do so — even though there is no scientific evidence whatsoever that ethylmercury causes autism.

    The form of mercury that you find in tuna fish, methylmercury, does bioaccumulate (and so anyone concerned about mercury build-up in their body may want to avoid eating tuna fish regularly).

    In a vaccine, you get around 10 to 25 micrograms of ethylmercury, which as stated does not bioaccumulate. But in a can of tuna, you will get around 40 micrograms of the methylmercury, which does bioaccumulate.

    Eating tuna once a month would thus be far worse that having a once monthly vaccine injection.

    So it seems to me that the banning of the Staphylococcus toxoid vaccine by in Sweden, due to concerns about mercury bioaccumulation, was not really warranted. Perhaps somebody needs to write to the Swedish government.



    Home Made Staphylococcus Toxoid Vaccine

    One thing I was looking at some time ago was making my own Staphylococcus toxoid vaccine.

    You can buy Staphylococcus alpha toxin from a number of suppliers, and what you would need to do, in order to inject it, is to sterilize this alpha toxin. But you need to use very high standards of sterilization, when it comes to injectables.

    You would also need to know the exact dosage of alpha toxin to put into each of the injections you make up yourself. I am not sure of how much alpha toxin goes into each injection of Staphylococcus toxoid vaccine.

    Some sellers of alpha toxin are here:

    Biological Laboratories, Inc.
    α-Hemolysin from Staphylococcus aureus lyophilized powder
    alpha-Toxin, Staphylococcus aureus | CAS 12616-52-3 | Calbiochem
    TOXIN, α HEMOLYSIN (02158522) - MP Biomedicals

    Though I would only want to make my own Staphylococcus toxoid vaccine if I could get advice from someone knowledgable about alpha toxin, and knowledgable about the right dosage, and knowledgable about how to properly sterilize a preparation to make it safe for injection.
     
  2. Ema

    Ema Senior Member

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  3. Hip

    Hip Senior Member

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    I don't think it is the same thing, unfortunately. I just looked up the word bacterin, and this is defined as "a suspension of killed or attenuated bacteria for use as a vaccine."

    So that veterinary vaccine will contain Staphylococcus bacteria, but probably not the Staphylococcus alpha toxin, which is what is required for treating ME/CFS.

    The general idea of toxoid vaccines (= vaccines that do not contain any bacteria, but just their toxins), is that in a bacterial infection, it is often the toxins synthesized by the bacteria which do much more harm than the bacteria themselves. So therefore, if you use a toxoid vaccine to create an antibody response against these bacterial toxins, if you did catch an infection from the bacteria, the infection will be must less harmful, as your immune system would know how to inactivate the bacterial toxins.

    The tetanus vaccine is an example of a toxoid vaccine: it contains bacterial toxins, but no actual bacteria.
     
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  4. redaxe

    redaxe

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    Is it possible for another toxoid vaccine to have the same benefit e.g. a tetanus booster?
     
  5. Hip

    Hip Senior Member

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    I don't think so, otherwise Professor Gottfries (himself an ME/CFS patient) and all those ME/CFS patients in Sweden who were greatly benefiting from the Staphylococcus toxoid vaccine would have switched to another toxoid vaccine.


    I think the mechanism of action of Staphylococcus toxoid vaccine is very specific: this vaccine has an immunomodulatory properties, and in particular, this study indicates that Staphylococcus toxoid vaccine corrects the immunodeficiency caused by coxsackievirus B3 infection.

    Now ME/CFS is strongly linked to coxsackievirus B, so if Staphylococcus toxoid vaccine corrects the immunodeficiency caused by coxsackievirus B, this may explain why this vaccine can be so beneficial for ME/CFS patients.

    Though I would like to know the precise mechanism by which Staphylococcus toxoid vaccine corrects the coxsackievirus B-induced immunodeficiency.


    Interestingly, Staphylococcus toxoid vaccine was used as a treatment as early as the 1930s, and this 1936 study found that Staphylococcus toxoid vaccine improved diabetes (and diabetes is also linked to, and I think likely caused by, coxsackievirus B infection).
     
    Last edited: Mar 6, 2014
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  6. Hip

    Hip Senior Member

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    An interesting study:

    Correction of immune response using purified staphylococcal toxoid and likopid in the secondary immunodeficiency induced by Coxsackie virus B3

    This study indicates that the immunomodulator drug Licopid was always able to correct the secondary (acquired) immunodeficiency caused by coxsackievirus B3 infection.

    By contrast, the study authors found that Staphylococcal toxoid was sometimes able to correct this secondary immunodeficiency, but sometimes it made it worse, depending on the experimental set-up the authors used.

    Licopid is a synthetic analogue of a cell wall component of all bacteria. The Russian name for this drug is Ликопид.

    More information about Licopid HERE (Google translated from Russian).


    I found Licopid for sale in these three pharmacies:
    Licopid 1mg
    Licopid 1mg tablets #10. Worldwide delivery

    Купить Ликопид тб. 1 мг №10


    This article mentions that Leukomeal, which is a "natural capsule form food version of Licopid" (whatever that means), has anecdotally been shown to improve quality of life for people with a wide variety of chronic degenerative diseases including ME/CFS.
     
    Last edited: Apr 27, 2014
  7. Ema

    Ema Senior Member

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    Are you going to try it?
     
  8. Hip

    Hip Senior Member

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    I might try it.

    I find it interesting that Licopid corrects the immune suppression caused by coxsackievirus B. I have often speculated that the herpes family virus reactivations found in many ME/CFS patients may in fact be due to coxsackievirus B immunosuppression (ie, that these herpes virus activations in ME/CFS are a secondary result of catching the immunosuppressive coxsackievirus B infection).

    So if you can correct this coxsackievirus B immunosuppression, this might also resolve any herpes family virus reactivations you have, and thus improve your health.

    I have tried three different Russian immunomodulators before (arbidol, tilorone and cycloferon), and did not notice any benefits, but those three were interferon boosters.

    However, Licopid works differently; it activates macrophages and neutrophils — see this study, and see also the Licopid data below:


    A company website with more info can be found here, and in particular, this pdf document from that website contains more details about Licopid; some of these details I have copied below:
    More info on the NOD2 receptor that Licopid activates in this Wikipedia article.
     
    Last edited: Apr 27, 2014
  9. golden

    golden Senior Member

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    Clear Light
    Does anyone here know what are the top 5 virus contenders? And where would you place coxsackie b3 in the runnings please?
     

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