The 12th Invest in ME Research Conference June, 2017, Part 2
MEMum presents the second article in a series of three about the recent 12th Invest In ME International Conference (IIMEC12) in London.
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Staph vaccine to treat CFS??

Discussion in 'Alternative Therapies' started by SpecialK82, May 4, 2010.

  1. Hip

    Hip Senior Member

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    It takes a while for the vaccine to start having an effect, so if you have stopped the vaccine and restarted, it might take some time for the benefits kick in. Benefits can begin to appear after as little as 2 weeks, but in other patients it can take several months for the benefits to appear.
     
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  2. CaptainA

    CaptainA

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    So, I just started the treatment and thought I would give some updates. Did the first injection last night and so far no rash. I woke up this morning with probably the most restful sleep I have had in years. I then crashed after taking the vitamin combination I do every day along with breakfast. Hoping to have more short updates as time goes on.
     
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  3. Omar88

    Omar88 Senior Member

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    hi

    where do you order it from ? and what it is the product name ?
    i have read that the vaccine they used before was stopped ? is there any other options ?
    does it work ? and how exactly is it working ?

    regards
     
  4. Abha

    Abha Abha

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    Hi Hip

    You mentioned somewhere that you were going to start a new thread on this topic.Have you done that? Also how is your vaccine treatment progressing.Thanks...
     
  5. Hip

    Hip Senior Member

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    I have had to temporarily halt my tests due to the fact that the vaccine now seems to have started triggering some mental symptom side effects each time I take it (these side effects only last for a day or two, but are a bit unpleasant, so I am stopping the test for the moment until I can find a way to prevent them).

    I have not yet got around to creating a new concise thread on the vaccine treatment, but some relevant posts in this thread are the following:

    Index to Important Posts in This Thread:

    The Russian Staphylococcus adsorbed vaccine seems to work similarly to the original Staphypan® Staphylococcus vaccine, which was used by Prof Gottfries as highly effective ME/CFS treatment proven in published clinical trials.

    Other Relevant Posts and Articles:


    @Omar88 have a look at the above threads: these should answer most of your questions.
     
    Last edited: Nov 18, 2017
  6. Abha

    Abha Abha

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  7. Sparrowhawk

    Sparrowhawk Senior Member

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    Thanks for the index -- as always, thorough and helpful as you are so consistently. Sorry to hear about the side effects and it will be important to see if any others report similar. Meanwhile sending you all the best for better outcomes with your next trial.
     
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  8. CaptainA

    CaptainA

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    Quick update #2

    Did the 3rd injection last night and I'm up to .3ml. For some reason this injection bled a lot and the injection site hurts more than normal the next day. Its also hard around the injection site. I'm thinking that this is due to the increased amount of the vaccine. Also, I'm not sure if I should be injecting slowly or quickly. @Hip maybe you can answer this question. I believe that I am receiving some benefit from the vaccine as I have had more energy in the mornings. I will note that I have started a 8/16 fasting schedule where I'm only eating within an 8 hour window with the exception of coffee mixed with butter. I've done this fast before with mixed results but now it seems to be really giving me some benefit. I would also like to note that I'm taking 1200 IU of D3 as Hip noted that his best days came when combining the D3 and the vaccine.

    I also can't help but think that the ampules I have just aren't that strong. The heat has been extreme and it took about 7 days to reach me. I wish there were a way to test the strength of the vaccine at home. Until next time...
     
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  9. Hip

    Hip Senior Member

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    I found that it is best to keep lateral movement of the needle to a minimum while injecting (ie, don't lever it sideways while it is in), else you can mildly injure the tissues beneath the skin surface with the sharp needle point, and this can irritate the injection site.



    I typically subcutaneously inject a 1 ml volume of liquid slowly over a period of 60 seconds or so. I will squeeze in around 20% of the liquid, then wait for 15 seconds, and then squeeze in another 20%, etc, until the whole 1 ml is injected.



    When I had these good weeks after injecting the vaccine, I was taking 12,000 IU (not 1,200 IU) daily of vitamin D3 for three weeks prior (it takes several weeks for vitamin D levels to build up in the body, so you really need to start taking vitamin D3 a few weeks prior to starting the injections).

    Interestingly enough, I recent learnt that good vitamin D3 status may be essential for low-dose naltrexone (LDN) to work: see Lack of vitamin D may reduce the efficacy of LDN.



    From what I can work out, toxoid-type vaccines like this Russian one, although they need to be stored in the refrigerator, are the most heat stable of all vaccines, and are the least likely to be damaged or weakened from being exposed to a period of higher temperatures. More details in the post: thermostability of vaccines.
     
    Last edited: Jul 20, 2017
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  10. CaptainA

    CaptainA

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    Ah, yes. I think I found this out the hard way. Just did the 4th injection and it went much smoother.

    I misspoke here. I was taking 12k. Thanks for catching that as I wouldn't want others to mess that up!

    Also, I just completed my 4th injection and stupidly only did .3cc instead of the .4cc so I'm hoping that my jump to .6cc next week won't be too bad.

    So far no big noticeable effects from the vaccine. My mood hasn't been too good lately and I'm beginning to suspect that this might be a cause.
     
  11. Hip

    Hip Senior Member

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    Originally I had noticed that the vaccine would put be into a buoyant, almost elated mood for a day or so just after injection (which was welcome, because usually I tend to be in the doldrums of mild depression). This temporary mood boost effect was reported by two others trying the vaccine (@Tinnybell and @ECAsson).

    Shame that you are not experiencing this, and may be getting a lowered mood instead. I understand that in Sweden, with the original Staphypan vaccine, the researchers did find some ME/CFS patients were sensitive to the mercury content. What I did at one stage was to take DMSA 300 mg three times daily in the days just after the injection; DMSA is a mercury chelator (which I just happened to have in stock).
     
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  12. Sparrowhawk

    Sparrowhawk Senior Member

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    @Hip the only counter to your advice above is (per Andrew Cutler) that folks with Mercury Amalgam fillings still in their mouths should not take DMSA or any other mercury chelator -- can unfortunately mobilize more mercury around the body and into the brain than you would help remove from the injections mercury content.
     
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  13. Hip

    Hip Senior Member

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    @Sparrowhawk, yes it did occur to me also that DMSA might make things worse rather than better. It's hard to tell. I don't think I am mercury sensitive anyway. And bear in mind that eating a can of tuna will deposit just as much mercury in your bloodstream as a vaccine injection.
     
  14. Sparrowhawk

    Sparrowhawk Senior Member

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    Right, and the gods know I ate way, way too much tuna over the years as a penniless grad student. :)
     
  15. ECAsson

    ECAsson

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    It's true. In the very beginning, I would feel awesome upon taking the shots, immediately. However, I became slightly worse after a couple of weeks of doing so (can't remember when exactly), and I got slightly worse overall ever since. I can't tell for sure if it had something to do with the vaccine or the nature of the infection.
     
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  16. TenuousGrip

    TenuousGrip Senior Member

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    Anybody ever had their IgG antibodies to staph tested ??

    I'm a carrier (nasal/sinus) of s.aureus. It seems nasal carriage should reflect elevated antibody levels*

    But if it doesn't, that could represent a significant immune defect.

    In May, I was tested for IgG antibodies to 23 strains of streptococcal pneumoniae. I made nearly zero antibodies to 22 of the 23 strains. This IS a problem.

    The normal next step would be a Pneumovax vaccine, followed by another blood test in 4-6wks. But I've had too many adverse drug and vaccine reactions to risk it.

    I'm currently working with an immunologic center of excellence on how to proceed on the s.pneumoniae defect, and will be asking them to do similar testing for staph.

    Incidentally, I've done the Bactroban/Mupirocin treatment thing several times. If it worked ... the staph colonization always comes back.

    If some of us have innate immune problems with such common bugs as staph and strep, that could definitely cause a lot of misery.

    ----

    * http://cvi.asm.org/content/17/7/1117.full
     
  17. Hip

    Hip Senior Member

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    I was informed that in the first weeks of the vaccine protocol, patients sometimes feel very slightly worse; but then the improvements in ME/CFS symptoms appear from around the two week point onwards, in those who respond to the vaccine.

    Though for some others, it takes months before they respond to the vaccine.
     
  18. CaptainA

    CaptainA

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    So just a quick update: Its now been over 3 month since I started the protocol and I'm now doing maintenance injections of 1ml every two weeks. I hadn't noticed much improvement until now. Its now been two days since the 1ml shot. The night after I did the injection I woke up and could not go back to sleep. It felt like I had energy and a clear head. I got terrible sleep but the next day and day after/today I've seen some marked improvement with mood, energy and brain fog. I would say that I feel 30-40% better than my baseline. Usually getting terrible sleep means a terrible next day but even with that I've seen great improvement.

    I also almost gave up on this treatment because it was past the 2 months but apparently some doctors are saying it can take longer. Hoping the effects stick around. I'll update on the progress soon.
     
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  19. Hip

    Hip Senior Member

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    That's similar to what I experienced with the vaccine when it was working for me: I'd inject the vaccine, and then on around the 3rd day after the injection, I noticed a major increase in mood, energy and mental clarity. So with my brain fog banished by the vaccine, I was able to do lots of complex computer programming work that I would normally never be able to do.

    Then after around 8 to 10 days in this energized and clear-headed state, these positive effects of the vaccine would slowly wear off; so it was then time for another injection, which again gave me another 8 to 10 days of great mental clarity and energy. More info here.
     
    Last edited: Sep 30, 2017
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  20. Abha

    Abha Abha

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    Hi CaptainA,
    Just wondering if you have made any further progress on this treatment...
    Thanks....
     

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