Tate Mitchell posted this to co-cure
http://www.ncbi.nlm.nih.gov/pubmed/21449012
Mov Disord. 2011 Mar 29. doi: 10.1002/mds.23563. [Epub ahead of print]
Decades of delayed diagnosis in 4 levodopa-responsive young-onset
monogenetic parkinsonism patients.
Ling H, Braschinsky M, Taba P, Ls SM, Doherty K, Hotter A, Poewe W, Lees AJ.
Reta Lila Weston Institute of Neurological Studies, Institute of
Neurology, University College London, London, United Kingdom; Queen
Square Brain Bank for Neurological Disorders and Institute of
Neurology, University College London, London, United Kingdom.
Abstract
BACKGROUND: We report 4 patients with young-onset monogenetic
parkinsonism, each of whom was misdiagnosed with either a psychogenic
movement disorder or chronic fatigue syndrome for 10 to 23 years after
the onset of their first symptoms.
RESULTS: Once the diagnosis was eventually made, they all had a rapid
and excellent response to levodopa, albeit with the early appearance
of interdose dyskinesias in 3.
CONCLUSIONS: We discuss possible reasons for the missed diagnosis
despite the relentless progression of their motor handicap. DAT
scanning supported the revised clinical diagnosis of parkinsonism.
2011 Movement Disorder Society.
Copyright 2011 Movement Disorder Society.
PMID: 21449012 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21449012
Mov Disord. 2011 Mar 29. doi: 10.1002/mds.23563. [Epub ahead of print]
Decades of delayed diagnosis in 4 levodopa-responsive young-onset
monogenetic parkinsonism patients.
Ling H, Braschinsky M, Taba P, Ls SM, Doherty K, Hotter A, Poewe W, Lees AJ.
Reta Lila Weston Institute of Neurological Studies, Institute of
Neurology, University College London, London, United Kingdom; Queen
Square Brain Bank for Neurological Disorders and Institute of
Neurology, University College London, London, United Kingdom.
Abstract
BACKGROUND: We report 4 patients with young-onset monogenetic
parkinsonism, each of whom was misdiagnosed with either a psychogenic
movement disorder or chronic fatigue syndrome for 10 to 23 years after
the onset of their first symptoms.
RESULTS: Once the diagnosis was eventually made, they all had a rapid
and excellent response to levodopa, albeit with the early appearance
of interdose dyskinesias in 3.
CONCLUSIONS: We discuss possible reasons for the missed diagnosis
despite the relentless progression of their motor handicap. DAT
scanning supported the revised clinical diagnosis of parkinsonism.
2011 Movement Disorder Society.
Copyright 2011 Movement Disorder Society.
PMID: 21449012 [PubMed - as supplied by publisher]