New era for ME/CFS research as top cytokine study attracts media headlines
The immune systems of patients who have recently developed ME/CFS look markedly different from those who have been ill for much longer, according to a major new study from Drs. Ian Lipkin and Mady Hornig at Columbia University. This shift in immune function hadn’t been seen before.
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Some methylation questions

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Johnmac, Jan 27, 2013.

  1. Johnmac

    Johnmac Senior Member

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    Southeast Asia
    I've been on the Rich von K simplified protocol for 5 weeks (very beneficial). Now I want to get a bit more detailed & methodical.

    I've got my 23andMe results, and have been through the Yasko book & Heartfixer site to determine what supps/diet changes to make, as workarounds for my SNPs. I've made a list of things to introduce - in 'Yasko order' (e.g. ACAT first). Questions:

    * So now I start introducing those things gradually, right?

    * Do I need every supplement for each SNP? For example ACAT needs Adenosyl B12, other forms of B12, low dose vit E succinate, a little Actofolate, CQ10, lactoferrin. SAMe, bile salts, GSH, curcumin, quercetin. For the sake of my wallet (& simplicity) could I (for example) forget about the quercetin, lactoferrin, bile salts and SAMe?

    * Typically, how long might I wait before I notice anything?

    * When do I move on to the next SNP?

    * Apart from my MAO-A (which is a simple +), all my SNPs are +/-. Most of the Yasko & Heartfixer recommendations are for people with +/+ SNPs. So do I just water down the prescriptions somewhat - take less?


    Any advice appreciated.

    Thanks,

    John

    FYI, I have these SNPs: ACAT, CBS, MTHFR, MTR, MTRR, BHMT, COMT, VDR (all +/-), and MAO-A (+).
     
  2. Lotus97

    Lotus97 Senior Member

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    United States
    Yeah, it would be a good idea to add things gradually. I know very little about SNP testing, but I am relatively confident that even if you have the exact same profile as someone else you might still react differently to the various supplements because there are so many variables that affect a person's body chemistry.
     
    Star-Anise likes this.

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