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Solve: Non-Invasive Diagnostic Test Project Seeks to Detect ME/CFS

Discussion in 'Latest ME/CFS Research' started by AndyPR, Jan 21, 2017.

  1. AndyPR

    AndyPR Tired Sam ate all the cookies!

    http://solvecfs.org/promising-non-invasive-diagnostic-testing-project-seeks-to-detect-mecfs/
     
    Cohen2, JaimeS, Valentijn and 13 others like this.
  2. eljefe19

    eljefe19

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    Someone tell me why this ISN'T a diagnostic test?
     
    belize44 likes this.
  3. Jonathan Edwards

    Jonathan Edwards Senior Member

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    Presumably because they have only tested one patient who differed from one normal in one respect. The next patient might not differ or might differ in another respect. A diagnostic test needs to show a consistent pattern.
     
    Zombie_Lurker, JaimeS, PatJ and 8 others like this.
  4. alex3619

    alex3619 Senior Member

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    There also need to be enough patients to have some statistical surety, comparison with likely alternate diagnoses, and a measure of specificity and sensitivity (95% or better is preferred, but sometimes this is relaxed if no other test exists). There are other potential tests being looked at, but none meet the full criteria. Of course, you then have to publish the findings.
     
  5. A.B.

    A.B. Senior Member

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    The researchers seem to be new to ME/CFS. :)
     
  6. eljefe19

    eljefe19

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    Exact What I was thinking
     
  7. Woolie

    Woolie Senior Member

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    Wouldn't you need a control group with similar levels of activity? Like super sedentary or something?
     
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  8. trishrhymes

    trishrhymes Senior Member

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    The proposed study looks interesting. They have not claimed the single case provides a diagnostic test, it is simply a starting point of interest.

    I assume they will use matched sedentary controls. Possibly also compare with people with other chronic fatiguing illnesses like MS.

    There's a long way to go, but I'm glad they are trying. The more interesting leads are followed up, the better chance of useful discoveries being made.
     
    Johannawj, JaimeS, MEMum and 10 others like this.
  9. PeeWee

    PeeWee

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    As I read it, this is a funded piece of research that is happening.It will now test the hypothesis formulated from its initial single patient comparison. It may result in a diagnostic test, a step towards one, or at least some advance in knowledge. Sounds great to me.
     
  10. JaimeS

    JaimeS Senior Member

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    Always. Wish all researchers would use sedentary controls.
     

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