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SOD mimetic inhibits immune response in cerebral malaria

Discussion in 'Other Health News and Research' started by cigana, Jun 24, 2014.

  1. cigana

    cigana Senior Member

    It is interesting how this suggests that immune activation can be inhibited by an enzyme that prevents oxidative stress:

    A user on this forum @Bluebrid has found this mimetic to be very helpful.
    AbbyDear likes this.
  2. Bluebrid


    Tempol is often used in research to test whether or not a condition is related to free radical stress. Interesting that Tempol attenuated the hyper-coagulation and inflammatory response to cerebral malaria. It is most likely due to the improved cell signaling.

    One of the infections I contracted prior to taking Tempol was severe babesiosis. Babesia is considered a “cousin” of malaria. Most people are able to clear babesia on their own. However with my genes, free radical stress and the toxins I had encountered, babesia was shutting down my immune system. The clotting issues were so bad, they thought I was having mini strokes -- and then I was hospitalized with a DVT and PEs. 2/3 of my lungs were full of clots by the time I got to the hospital.

    In retrospect, the integrative MD said that the SOD SNP is most likely the reason I was not able to handle the babesiosis without intervention. As I had not yet found Tempol -- and it took over 6 months of high dose malaria meds to clear the infection. The meds, infections and clotting issues definitely took a toll on my body.
    AbbyDear, merylg and cigana like this.

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