Hi all, I've been messing around with methylation supports and related co-factors for more than a year now with good success. Most of my symptoms have improved dramatically. However, one large issue still remains. I often find that if even remotely stimulated, embarrassed, stressed, etc. in social situations, I turn bright red, panic and often begin sweating - essentially the epitome of fight or flight. At this point, I'm trying to figure out which of the following is the culprit: Overmethylation (I have COMT/MAO-A mutations as well) Copper/Mercury/heavy metal dumping Histamine reaction Something relating to Pyroluria (been tested, came back normal but I've read the test may not be accurate even when directions are followed - I've had great success with Zinc/P5P/B6 but they oddly simultaneously seem to make these issues worse which leads me to believe it may be Copper dumping). Any advice or experiences would be greatly appreciated. Thank you in advance.