Does any one have it? (or family members having bipolar, schitz, or social anxiety) Social anxiety disorder is a chronic mental health condition that causes an irrational anxiety or fear of activities or situations in which you believe that others are watching you or judging you. You also fear that you'll embarrass or humiliate yourself. Some research suggests that a structure in the brain called the amygdala may play a role in controlling the fear response. I realize this is a narrow question, but I'm asking because I suffer from it--and had it long before I developed CFS. I feel that my genetics are involved here.