A few weeks ago I started the SMP but I can't say I have noticed any of the healing effects that others have experienced. The only things I have noticed is that on a relatively high dosage of the mb12 (5000mcg sublingual) I become overwhelmed by the need to nap. This is in contrast to a couple of years ago when the same mb12 would cause the opposite effects (anxiety, restlessnes, insomnia etc). The main change compared to then, is that I have had a few amalgams removed and may be some mercury is floating around (as well as Naet treatment for the supplements). I read that mb12 can interact with mercury so I stopped experimenting with that and I just take Hydroxy B12 2000mcg. In addition I take Thorne B complex (includes 200mcg folinic, 200mcg methylfolate). So my question is the following. I have a low methylation capacity (SAM/SAH= 4.3; SAM=220) but folate and mb12 are normal, albeit on the low side (5-CH3-TF=26; Mb12=116; levels with no supplementation) would the SMP raise methylation just by the addition of more of the folate and B12? or other action would be needed?