Lotus, So which studies do you want to ignore the science of. Hundreds of studies including the pharmacodynamics of cobalamins? That is overwhelming and they all more or less agree. The differences make no practical differences in what we are discussing here. Do you want to ignore the studies that link monomethymercury to symptoms? Do you want to ignore the serum halflifes determined in many studies in animals and fish as 71-72 days? How about the studies that measured the serum halflif as the study itself and determined 71-72 days? You want to ignore those? Sure there are studies IN TEST TUBES of reacting mercury to high concentration MeCbl, proving it is possible for them to react but say nothing about in the body combining. The amount of excreted unchanged cobalamin studies, of all forms, is VERY CLEAR. There isn't any wiggle room. 1% remains 24-48 hours after injection. That amounts to 5mg sublingual held for a couple of hours or a 1mg injection. That still amounts to 10mcg availalbe for reactions of ALL sorts, conversion to AdoCbl, reaction with mercury, reactions with folate, etc. Within the constraints of hundreds of prior studies, that means that from 1mg of MeCbl absorbed daily that the amnount of monomethylmercury that can be generated is 1.4 mcg which mathamatically works out to be the amount in 1 -2 grams of fish containing the higher amounts of methyl mercury. It is hardly a hypothesis. It is merely a little math putting together the separate data from multiple studies. Now if you can show me where the holes are in my model and why that is not correct I will certainly learn. What studies are you going to change or ignore to come to other conclusions to support it. Right now all I see is a belief in the magical powers of MeCbl, just whisper that potent name and monomethylmercury, which is SPECIFICALLY the only form we are discussing, pours into the tissues in such large amounts so quickly it would have required 210mg of MeCbl to be consumed 100% with zero excreted unchanged in forming that amount of monomethylmercury to casue toxic symptoms. I DON"T BELIEVE IT. That hypothesis would require complete rejection of all those hundreds of papers on 4 topics.