Wow! A while ago some of y'all suggested that my horrible histamine reactions might be due to too much methylation going on but when I cut way back on my methylation supps OMG, I coulldn't think at all!! It was amazing what a huge difference it was. I was always loosing and dropping things and couldn't remember anything. I do think that cutting back reduced the histamine reactions a little, but not enough to give up cognitive function. Whatever the histamine issue is, I have to find a solution that will let me stay on my methylation supps.